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So far afreis@fc.ul.pt has created 40 blog entries.

BioISI Researchers published two papers in two prestigious international journals

2019-06-07T17:18:00+00:00 June 7th, 2019|

Researchers from BioISI's Chemistry for Biological Systems Group (Computational Chemistry Lab led by Paulo J. Costa ) published two papers in two prestigious international journals, one in Expert Opinion on Drug Discovery, the other in the  Journal of Chemical Theory and Computation  In these,  Paulo J. Costa, Diogo Vila Viçosa e Rafael Nunes discuss and [...]

1st BioISI PhD Symposium

2019-10-04T11:33:41+00:00 June 7th, 2019|

Lisboa (Portugal) 28 June 2019 We are planning a special day to gather and share some science. We will catch up on our latest results and have some time to celebrate. We want to invite all the community to join us and so have a fruitful discussion. It will take place on Auditório do Caleidoscópio, [...]

Tyrosine phosphorylation modulates cell surface expression of chloride cotransporters NKCC2 and KCC3

2019-06-06T16:52:35+00:00 June 6th, 2019|

Cláudia AlmeidaLoureiro, PatríciaBarros, PauloMatos, PeterJordan Cellular chloride transport has a fundamental role in cell volume regulation and renal salt handling. Cellular chloride entry or exit are mediated at the plasma membrane by cotransporter proteins of the solute carrier 12 family. For example, NKCC2 resorbs chloride with sodium and potassium ions at the apical membrane [...]

Halogen bonding in halocarbon-protein complexes and computational tools for rational drug design

2019-06-06T16:38:01+00:00 June 6th, 2019|

Paulo J. Costa, Rafael Nunes & Diogo Vila-Viçosa (2019) Halogen bonding in halocarbon-protein complexes and computational tools for rational drug design,Expert Opinion on Drug  Discovery Introduction: Halogens have a prominent role in drug design. Often used as a mean to improve ADME properties, they are also becoming a tool in protein–ligand recognition given their [...]

BioISI Post Graduate Seminars, May 21, FCUL

2019-06-07T16:54:14+00:00 May 15th, 2019|

Room 1.3.33 A- May 21, 17h Miguel Vitorino  DAEPHYS PhD student, Bio-PhysNano Going nano: exploring biological physics through atomic force microscopy Atomic force microscopes (AFMs) had a critical role in the exploration of the nanoscale over the last decades. In particular, they are fundamental to the latest interdisciplinary effort [...]

2019 Summer School on Epithelial Systems: Physiology and Pathophysiology

2019-05-27T09:52:30+00:00 April 12th, 2019|

Lisboa (Portugal) 22 – 26 July 2019 FREE REGISTRATION! DEADLINE FOR REGISTRATION EXTENDED: JUNE 12  Limited registrations: 20 participants Learn about the latest developments on Epithelial Systems: Physiology and Pathophysiology and discuss your project with the experts Workshop Overview Participants will learn about the latest developments in Epithelial Systems: Physiology and Pathophysiology. Besides the opportunity to discuss [...]