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COVID-19 Research @ BioISI

2020-07-29T10:59:41+00:00 July 29th, 2020|

Ganna Rozhnova is a Researcher from BioISI's Bio-PhysNano Group and works in epidemiological modeling in The Netherlands. Ganna recently published an article in PLoS Medicine regarding the impact of preventive measures (self-imposed and governmental) on the dynamics of COVID-19 disease spread. Ganna is currently the PI of an FCT funded project within the [...]

Testing for COVID-19 at CIÊNCIAS

2020-07-29T10:55:56+00:00 June 12th, 2020|

CIÊNCIAS and BioISI are once again associated with an initiative to fight COVID-19. Coordinated by BioISI's integrated member Ricardo Dias, a Center for COVID Testing was installed at the TecLabs building. This Center is entirely dedicated to the mitigation of COVID-19 - virus screening and immunological tests - but will potentially serve future [...]

Fighting COVID-19 at BioISI

2020-04-24T14:58:28+00:00 April 21st, 2020|

BioISI integrated member and Microscopy Technician Luís Marques took the initiative to use the 3D print available at the Microscopy Unit to print holders for the visors used by healthcare professionals, in response to a plea from Instituto Superior Técnico in the face of this COVID-19 outbreak. The 3D printer used for this [...]

Marine Bioresource Development – Stakeholder’s Challenges, Implementable Actions, and Business Models

2020-02-13T11:02:15+00:00 February 13th, 2020|

Jane Eva Collins, Thomas Vanagt, Isabelle Huys and Helena Vieira Growth of the blue bioeconomy has potential for contributing positively toward economic growth, societal needs and multiple United Nations Sustainable Development Goals. However, organizations currently experience many challenges which limit success in this field. The aim of this paper is to identify trends in [...]

CO2 conversion to phenyl isocyanates by uranium(VI) bis(imido) complexes

2019-12-10T17:54:41+00:00 December 9th, 2019|

Leonor Maria, Nuno Bandeira, Joaquim Marçalo, Isabel Cordeiro Santos, and John K Gibson Uranium(VI) trans-bis(imido) complexes [U(κ4-{(tBu2ArO)2Me2-cyclam})(NPh)(NPhR)] react with CO2 to eliminate phenyl isocyanates and afford uranium(VI) trans-[O=U=NR]2+ complexes, including [U((κ4-{(tBu2ArO)2Me2-cyclam})(NPh)(O)] that was crystallographically characterized. DFT studies indicate that the reaction proceeds by endergonic formation of a cycloaddition intermediate; the secondary reaction to form [...]

Dynamical Rearrangement of Human Epidermal Growth Factor Receptor 2 upon Antibody Binding: Effects on the Dimerization

2019-12-09T15:16:17+00:00 December 6th, 2019|

Pedro R. Magalhães, Miguel Machuqueiro, José G. Almeida, André Melo, M. Natália D. S. Cordeiro, Sandra Cabo Verde, Zeynep H. Gümüş, Irina S. Moreira, João D. G. Correia, and Rita Melo Human epidermal growth factor 2 (HER2) is a ligand-free tyrosine kinase receptor of the HER family that is overexpressed in some of the [...]

Bioactivities of Centaurium erythraea (Gentianaceae) Decoctions: Antioxidant Activity, Enzyme Inhibition and Docking Studies

2019-12-09T15:11:33+00:00 December 6th, 2019|

Laura Guedes, Pedro B. P. S. Reis, Miguel Machuqueiro, Asma Ressaissi, Rita Pacheco, and Maria Luísa Serralheiro Centaurium erythraea is recommended for the treatment of gastrointestinal disorders and to reduce hypercholesterolemia in ethno-medicinal practice. To perform a top-down study that could give some insight into the molecular basis of these bioactivities, decoctions from C. [...]

The rapid electrochemical activation of MoTe2 for the hydrogen evolution reaction

2019-11-05T13:21:03+00:00 November 4th, 2019|

Jessica C. McGlynn, Torben Dankwort, Lorenz Kienle, Nuno A. G. Bandeira, James P. Fraser, Emma K. Gibson, Irene Cascallana-Matías, Katalin Kamarás, Mark D. Symes, Harry N. Miras & Alexey Y. Ganin The electrochemical generation of hydrogen is a key enabling technology for the production of sustainable fuels. Transition metal chalcogenides show considerable promise as [...]