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BioISI Research Day 2020
BioISI Research Day 2020bioisidirector@fc.ul.pt2020-12-09T15:22:07+00:00

BioISI Day Programme

26th November 2020

‘click on each title to open respective video’

 

09:30 – 10:00 – Welcome address by Margarida Amaral & Institutional Video

10:00 – 10:30 – BioISI Facilities

  • Rui Malhó: Introducing the BioISI facilities
  • Rui Malhó: Microscopy facility
  • Hugo Botelho: Screening facility
  • Luísa Serralheiro: Mass Spec facility
  • Margarida Gama-Carvalho: Genomics facility

10:30 – 11:00 – Coffee Break          

11:00 – 12:00 – Internal collaborative BioISI projects – Chair: Manuela Pereira

  • Federico Herrera: Restoring NKX6-2 function by protein complementation: a proof-of-concept.
  • Bárbara Henriques: Multidisciplinary approach to study post-translational modifications in metabolic enzymes.
  • Inna Uliyakina: Exploring the impact of Staphylococcus aureus on Cystic Fibrosis epithelial cell inflammation, differentiation and epithelial repair.
  • Ana Catarina Alves: Novel mechanisms causing Familial Hypercholesterolaemia: Functional characterization of variants in the regulatory regions of PCSK9 and LDLR genes.
  • Rita Pacheco: VALHealth- Valorisation of ALgae for Health: Bioactive Compounds from Marine Bioresources by Membrane Technology.

14:00 – 15:00 – Bioindustry partnership projects – Chair: Rui Malhó

  • Anabela Bernardes da Silva: GOJIBERRIES and OPTIMAL – Partnerships for fruit Bioindustry
  • Nuno A. G. Bandeira: SMARTMEM – Computational modelling for improved photo-activated detergent microcapsules
  • Daniela Ferreira: PulmaGene – Genetic blood testing of cancer therapies
  •  Paula Martins-Lopes: INNOVINE&WINE and INTERACT – Partnerships for the wine sector
  • Iris Silva: HIT-CF – Personalised Treatment for Cystic Fibrosis Patients 

15:00 – 15:15 – Short Break

15:15 – 16:15 – Selected BioISI papers 2020 – Chair: Paulo Costa

  • Margarida Quaresma: Mutant CFTR Drives TWIST1 Mediated Epithelial-Mesenchymal Transition
  • Manuela R. Costa: Genome-Wide Identification of Epigenetic Regulators in Quercus suber L.
  • Mário Rodrigues: Mechanical Properties of Human Bronchial Epithelial Cells Expressing Wt-and Mutant CFTR
  • Hugo Martiniano: Identification of biological mechanisms underlying a multidimensional ASD phenotype using machine learning
  • Elisabete R. Silva: Biofouling Inhibition with Grafted Econea Biocide: Toward a Nonreleasing Eco-Friendly Multiresistant Antifouling Coating

16:15 – 16:30 – Short Break

16:30 – 17:30 – PhD presentation pitches – Chair: Margarida Amaral

  • Joana V Ribeiro: Molecular Insights into Riboflavin Supplementation in Glutaric Aciduria Type I Patients
  • Lúcia Santos: CRISPR/Cas9 genome editing as a therapeutic approach for Cystic Fibrosis
  • Madalena Pinto Personalised Therapies for All: Restoring Airway Function in Cystic Fibrosis by Stimulation of Alternative Chloride Channels
  • Fernanda Ferreira: Ataxia related protein sacsin knockout disrupts the intermediate filaments network in glial cells
  • Rafael Nunes: Can membrane-drug interactions be mediated by halogen bonds?
  • Rebeca André: Effect of Fucus vesiculosus aqueous extract on cholesterol synthesis and absorption
  • Pedro Reis: PypKa: a python module for flexible Poisson-Boltzmann based pKa calculations
  • Flávio Soares: CRISPR/Cas9-mediated mutagenesis of SlGRAS10: role during tomato fruit development and ripening 
  • Ana Alves: Characterization of selected miRNAs during conifer embryo development
  • Dario Marchese: Functional analysis of Phosphoinositides and lipid kinases in pollen tube apical growth
  •  Ana Reis: Multi-Host Tuberculosis: from Pathogen Genomics to Transmission Dynamics
  • Diogo Pereira: Fungal biodiversity tendencies on palms’ diseases spots
  • Pedro Jorge Dias Teixeira: Adaptive evolution (h)as the key
  • João Pedro Xavier dos Santos: Gene-environment interactions in Autism Spectrum Disorder
  • Joana Vilela: Role of neurotransmission and synaptic processes in Autism Spectrum Disorder
  • Joana Chora: Personalized Medicine in Familial Hypercholesterolemia
  • Juan F. García-Moreno: The involvement of DIS3L2 in nonsense-mediated mRNA decay and its functional networks in cancer  
  • Joana Pereira: Stromal cell-derived cytokine signals promote the expression of tumor-related alternative splicing variant RAC1B in polarized intestinal cells
  • Tânia Marques: An integrative approach to tissue-specific effects of microRNA regulatory networks

 17:30 – Closing Remarks by Margarida Amaral

CONTACTS

BioISI – BioSystems and Integrative Sciences Institute
Faculdade de Ciências da Universidade de Lisboa
Campo Grande, 1749-016 Lisboa
PORTUGAL

Telephone: +351 217 500 857

Sponsored by:

FCT logo

Financed by national funds thought FCT – Fundação para a Ciência e a Tecnologia, I.P., under the following project references:

UID/Multi/04046/2013

UID/Multi/04046/2019

UIDB/04046/2020

UIDP/04046/2020

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