BioISI Day Programme
26th November 2020
‘click on each title to open respective video’
09:30 – 10:00 – Welcome address by Margarida Amaral & Institutional Video
10:00 – 10:30 – BioISI Facilities
- Rui Malhó: Introducing the BioISI facilities
- Rui Malhó: Microscopy facility
- Hugo Botelho: Screening facility
- Luísa Serralheiro: Mass Spec facility
- Margarida Gama-Carvalho: Genomics facility
10:30 – 11:00 – Coffee Break
11:00 – 12:00 – Internal collaborative BioISI projects – Chair: Manuela Pereira
- Federico Herrera: Restoring NKX6-2 function by protein complementation: a proof-of-concept.
- Bárbara Henriques: Multidisciplinary approach to study post-translational modifications in metabolic enzymes.
- Inna Uliyakina: Exploring the impact of Staphylococcus aureus on Cystic Fibrosis epithelial cell inflammation, differentiation and epithelial repair.
- Ana Catarina Alves: Novel mechanisms causing Familial Hypercholesterolaemia: Functional characterization of variants in the regulatory regions of PCSK9 and LDLR genes.
- Rita Pacheco: VALHealth- Valorisation of ALgae for Health: Bioactive Compounds from Marine Bioresources by Membrane Technology.
14:00 – 15:00 – Bioindustry partnership projects – Chair: Rui Malhó
- Anabela Bernardes da Silva: GOJIBERRIES and OPTIMAL – Partnerships for fruit Bioindustry
- Nuno A. G. Bandeira: SMARTMEM – Computational modelling for improved photo-activated detergent microcapsules
- Daniela Ferreira: PulmaGene – Genetic blood testing of cancer therapies
- Paula Martins-Lopes: INNOVINE&WINE and INTERACT – Partnerships for the wine sector
- Iris Silva: HIT-CF – Personalised Treatment for Cystic Fibrosis Patients
15:00 – 15:15 – Short Break
15:15 – 16:15 – Selected BioISI papers 2020 – Chair: Paulo Costa
- Margarida Quaresma: Mutant CFTR Drives TWIST1 Mediated Epithelial-Mesenchymal Transition
- Manuela R. Costa: Genome-Wide Identification of Epigenetic Regulators in Quercus suber L.
- Mário Rodrigues: Mechanical Properties of Human Bronchial Epithelial Cells Expressing Wt-and Mutant CFTR
- Hugo Martiniano: Identification of biological mechanisms underlying a multidimensional ASD phenotype using machine learning
- Elisabete R. Silva: Biofouling Inhibition with Grafted Econea Biocide: Toward a Nonreleasing Eco-Friendly Multiresistant Antifouling Coating
16:15 – 16:30 – Short Break
16:30 – 17:30 – PhD presentation pitches – Chair: Margarida Amaral
- Joana V Ribeiro: Molecular Insights into Riboflavin Supplementation in Glutaric Aciduria Type I Patients
- Lúcia Santos: CRISPR/Cas9 genome editing as a therapeutic approach for Cystic Fibrosis
- Madalena Pinto Personalised Therapies for All: Restoring Airway Function in Cystic Fibrosis by Stimulation of Alternative Chloride Channels
- Fernanda Ferreira: Ataxia related protein sacsin knockout disrupts the intermediate filaments network in glial cells
- Rafael Nunes: Can membrane-drug interactions be mediated by halogen bonds?
- Rebeca André: Effect of Fucus vesiculosus aqueous extract on cholesterol synthesis and absorption
- Pedro Reis: PypKa: a python module for flexible Poisson-Boltzmann based pKa calculations
- Flávio Soares: CRISPR/Cas9-mediated mutagenesis of SlGRAS10: role during tomato fruit development and ripening
- Ana Alves: Characterization of selected miRNAs during conifer embryo development
- Dario Marchese: Functional analysis of Phosphoinositides and lipid kinases in pollen tube apical growth
- Ana Reis: Multi-Host Tuberculosis: from Pathogen Genomics to Transmission Dynamics
- Diogo Pereira: Fungal biodiversity tendencies on palms’ diseases spots
- Pedro Jorge Dias Teixeira: Adaptive evolution (h)as the key
- João Pedro Xavier dos Santos: Gene-environment interactions in Autism Spectrum Disorder
- Joana Vilela: Role of neurotransmission and synaptic processes in Autism Spectrum Disorder
- Joana Chora: Personalized Medicine in Familial Hypercholesterolemia
- Juan F. García-Moreno: The involvement of DIS3L2 in nonsense-mediated mRNA decay and its functional networks in cancer
- Joana Pereira: Stromal cell-derived cytokine signals promote the expression of tumor-related alternative splicing variant RAC1B in polarized intestinal cells
- Tânia Marques: An integrative approach to tissue-specific effects of microRNA regulatory networks
17:30 – Closing Remarks by Margarida Amaral