GER – Gene Expression and Regulation
BioISI Digest | Grapevine-Associated Lipid Signalling Is Specifically Activated in an Rpv3 Background in Response to an Aggressive P. viticola Pathovar
A recent paper, first-authored by Gonçalo Laureano and headed by Andreia Figueiredo, presents a study using a Plasmopara viticola strain capable of supress the defence mechanisms conferred by a specific defence gene, the Rpv3, in grapevine. Read the BioISI Digest below to know more.
Bio[r]SciDE – Science Days and Ephemeris | International Women’s Day
On this International Women's Day, we are challenged to embrace equity. Ciência Viva recognizes several Portuguese women devoted to Science in a new edition of the book “Women in Science”, which includes the portrait of 101 female researchers in different scientific fields. Get to know below the testimonials of three BioISI female researchers who have been recognized in this book.
Carlos Farinha has been awarded by Emily’s Entourage to develop a novel approach to potentially treat Nonsense Mutations of Cystic Fibrosis
Carlos Farinha has been awarded 220 thousand USD by Emily’s Entourage to support research on restoring CFTR protein function in people with Cystic Fibrosis bearing nonsense mutations.
BioISI Digest | Rescue of Rare CFTR Trafficking Mutants Highlights a Structural Location-Dependent Pattern for Correction
A new paper, first-authored by Sónia Zacarias, coordinated by Carlos M. Farinha, with the collaboration of Bruno L. Victor, reveals the mode of action of different drugs on the deffective protein that causes Cystic Fibrosis, giving valuable insights to develop new therapies for individuals bearing rare variants . Know more on this BioISI Digest.
Bio[r]SciDE – Science Days and Ephemeris | Rare Disease Day
On this day Rare Disease Day, we want to tell you one chapter of the rare diseases ‘research story. BioISI scientists are the main characters, their research is the argument and the message they want to convey is that Science contributes to equitable access to diagnosis, treatment, health and social care and opportunities for people suffering from a rare disease.
BioISI Digest | Mutation-class dependent signatures outweigh disease-associated processes in cystic fibrosis cells
A new paper, first-authored by Lúcia Santos and coordinated by Carlos M. Farinha, analyzes five different mutations in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene and the associated mechanisms that causes disease. Know more in this BioISI Digest.